{"created":"2023-05-15T12:36:18.731836+00:00","id":152,"links":{},"metadata":{"_buckets":{"deposit":"5e24eee8-27ad-4d42-8c92-c3e7aff06ea9"},"_deposit":{"created_by":7,"id":"152","owners":[7],"pid":{"revision_id":0,"type":"depid","value":"152"},"status":"published"},"_oai":{"id":"oai:shonan-ums.repo.nii.ac.jp:00000152","sets":["1"]},"author_link":["469","470","472","468","473","474","471","475"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019 Nov","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"765","bibliographicPageStart":"760","bibliographicVolumeNumber":"85","bibliographic_titles":[{},{"bibliographic_title":"Brazilian journal of otorhinolaryngology","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Chronic rhinosinusitis with nasal polyps is a heterogeneous disease and appropriate diagnostic algorithms in individual cases are necessary for effective medical treatment.","subitem_description_type":"Abstract"},{"subitem_description":"The purpose of this study was to clarify the relationship between the pendrin expression of nasal polyps and clinical and pathological characteristic features of eosinophilic chronic rhinosinusitis.","subitem_description_type":"Abstract"},{"subitem_description":"A total of 68 patients were classified into eosinophilic chronic rhinosinusitis or non-eosinophilic chronic rhinosinusitis groups according to the degree of eosinophilic infiltration into the nasal polyps. Clinical, hematological, and immunohistochemical analyses were performed and statistically compared between both groups.","subitem_description_type":"Abstract"},{"subitem_description":"Thirty-eight were classified into eosinophilic chronic rhinosinusitis and 30 into non-eosinophilic chronic rhinosinusitis groups. There were no significant differences in age distribution, sex ratio, prevalence of asthma, or any other complications between the groups. The mean Lund-Mackay score and the number of serum eosinophils was significantly higher in the eosinophilic chronic rhinosinusitis than in the non-eosinophilic chronic rhinosinusitis groups. The pendrin expression was more frequently detected in the epithelial surface layer of nasal polyps in the eosinophilic chronic rhinosinusitis than in the non-eosinophilic chronic rhinosinusitis groups. In addition, mucin 5AC was more widely expressed in the eosinophilic chronic rhinosinusitis than in the non-eosinophilic chronic rhinosinusitis.","subitem_description_type":"Abstract"},{"subitem_description":"Increased expression of pendrin and mucin 5AC in the nasal polyps would be associated with development of eosinophilic chronic rhinosinusitis. This finding could allow the development of a novel therapeutic agent targeted specifically to patients with eosinophilic chronic rhinosinusitis.","subitem_description_type":"Abstract"}]},"item_10001_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Chronic rhinosinusitis with nasal polyps is a heterogeneous disease and appropriate diagnostic algorithms in individual cases are necessary for effective medical treatment.","subitem_description_type":"Other"},{"subitem_description":"The purpose of this study was to clarify the relationship between the pendrin expression of nasal polyps and clinical and pathological characteristic features of eosinophilic chronic rhinosinusitis.","subitem_description_type":"Other"},{"subitem_description":"A total of 68 patients were classified into eosinophilic chronic rhinosinusitis or non-eosinophilic chronic rhinosinusitis groups according to the degree of eosinophilic infiltration into the nasal polyps. Clinical, hematological, and immunohistochemical analyses were performed and statistically compared between both groups.","subitem_description_type":"Other"},{"subitem_description":"Thirty-eight were classified into eosinophilic chronic rhinosinusitis and 30 into non-eosinophilic chronic rhinosinusitis groups. There were no significant differences in age distribution, sex ratio, prevalence of asthma, or any other complications between the groups. The mean Lund-Mackay score and the number of serum eosinophils was significantly higher in the eosinophilic chronic rhinosinusitis than in the non-eosinophilic chronic rhinosinusitis groups. The pendrin expression was more frequently detected in the epithelial surface layer of nasal polyps in the eosinophilic chronic rhinosinusitis than in the non-eosinophilic chronic rhinosinusitis groups. In addition, mucin 5AC was more widely expressed in the eosinophilic chronic rhinosinusitis than in the non-eosinophilic chronic rhinosinusitis.","subitem_description_type":"Other"},{"subitem_description":"Increased expression of pendrin and mucin 5AC in the nasal polyps would be associated with development of eosinophilic chronic rhinosinusitis. This finding could allow the development of a novel therapeutic agent targeted specifically to patients with eosinophilic chronic rhinosinusitis.","subitem_description_type":"Other"}]},"item_10001_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"30126769","subitem_relation_type_select":"PMID"}}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.bjorl.2018.07.005","subitem_relation_type_select":"DOI"}}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1808-8686","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ito, Taku","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"468","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ikeda, Satoshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"469","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Asamori, Tomoaki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"470","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Honda, Keiji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"471","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kawashima, Yoshiyuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"472","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kitamura, Ken","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"473","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suzuki, Keiko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"474","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsutsumi, Takeshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"475","nameIdentifierScheme":"WEKO"}]}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Adolescent","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Adult","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Aged","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Aged, 80 and over","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Asthma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Chronic Disease","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Cytokines","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Eosinophilia","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Eosinophils","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Female","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Humans","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Male","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Middle Aged","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Nasal Polyps","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"RNA, Messenger","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Rhinitis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Sinusitis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Sulfate Transporters","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Young Adult","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Increased expression of pendrin in eosinophilic chronic rhinosinusitis with nasal polyps.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Increased expression of pendrin in eosinophilic chronic rhinosinusitis with nasal polyps.","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"7","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-06-01"},"publish_date":"2020-06-01","publish_status":"0","recid":"152","relation_version_is_last":true,"title":["Increased expression of pendrin in eosinophilic chronic rhinosinusitis with nasal polyps."],"weko_creator_id":"7","weko_shared_id":-1},"updated":"2023-05-15T12:39:51.389204+00:00"}